25 port is blocked in all servers by default.
To open it, you must provide an explanation of this port usage and please answer these questions:
1) What kind of emails do you plan to send?
2) How many emails do you plan to send per day?
Also, Time4VPS does not allow spamming and/or mass mailing, and we consider this activity a violation of our TOS.
If you have provided the explanation of 25 port usage to Bot, please ask to forward this chat to Human support because only Human support can unblock 25 port.
Other ports are managed manually by the VPS owner.